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What is DNA?

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Every cell in every living thing (or organism) has DNA, a molecule that contains all the information about that organism. Building on research by others before them, the structure of DNA was discovered in 1953 by the British scientist Francis Crick and the American scientist James Watson. James Watson was a World Almanac reader as a kid.

Lengths of connected DNA molecules, called genes, are tiny pieces of a code. They determine what each organism is like in great detail. Almost all the DNA and genes come packaged in thread-like structures called chromosomes--humans have 46. There are 22 almost identical pairs, plus the X and Y chromosomes, which determine if a human is male (one X chromosome and one Y chromosome) or female (two X chromosomes).

Genes are passed on from parents to children, and no two organisms (except clones and identical twins) have the same DNA. Many things--the color of our eyes or hair, whether we're tall or short, our chances of getting certain diseases--depend on the genes we get from our parents.

DNA is located in each of your cells, including your blood, saliva, hair follicles, and skin. No one else has a DNA pattern exactly like yours. For these reasons, DNA evidence can be collected from skin or hair collected a crime scene and then be linked to a suspect. Scientists can analyze the exact makeup of the two sets of DNA, and if they are identical, chances are that they are from the same person. Cells from a person at a crime scene can be evidence enough to convince a jury that that person was present at the crime.

DNA evidence is also helping show that some wrongly accused and convicted people are innocent. Since 1992, DNA evidence has helped reverse at least 78 convictions (including 10 cases where the death penalty was involved). In January 2001, a man imprisoned for murder in Texas was released because of DNA tests. Another man, sentenced to death for a murder in Virginia in 1982, was set free in February. New evidence based on DNA tests cleared him of the crime.

Parental testing is the use of genetic fingerprinting to determine whether two individuals have a biological parent-child relationship. A paternity test establishes genetic proof whether a man is the biological father of an individual, and a maternity test establishes whether a woman is the biological mother of an individual. Though genetic testing is the most reliable standard, older methods also exist including ABO blood group typing, analysis of various other proteins and enzymes, or using human leukocyte antigen antigens. The current techniques for paternal testing are using polymerase chain reaction (PCR) and restriction fragment length polymorphism.

DNA testing is currently the most advanced and accurate technology to determine parentage. In a DNA parentage test, the probability of parentage is 0% when the alleged parent is not biologically related to the child and the probability of paternity typically greater than 99.9% when the alleged parent is biologically related to the child.


Legal Testing                                                                                                                      The DNA parentage test that follows strict chain of custody can generate legally admissible results that are used for child support, inheritance, social welfare benefits, immigration, or adoption purposes. To satisfy the chain-of-custody legal requirements, all tested parties have to be properly identified and their specimens collected by a third party professional who is not related to any of the tested parties and has no interest in the outcome of the test.

Immigration Testing                                                                                                              In recent years, immigration authorities in various countries such as U. S, U. K. Canada, Australia, France and others have been requesting immigration petitioners and beneficiaries in a family-based immigration case to voluntarily take the DNA parentage test when primary documents such as birth certificate to prove biological relationship are missing or inadequate.

In the U. S., the immigration applicants bear the complete responsibilities of arranging and paying for DNA testing. The U. S. immigration authorities strictly require that the DNA test, if pursued, be performed by one of the laboratories accredited by the AABB (formerly American Association of Blood Banks). There are 38 accredited DNA family relationship testing laboratories on the AABB list. [3] Most labs have a collection network throughout the country. There is currently no accredited DNA lab in the largest immigrants’ destination New York, and there is one accredited laboratory – Universal Genetics [4]in the second largest destination Los Angeles.

The U. S. Department of State and USCIS both provide clear information on their websites concerning the DNA parentage test request for immigration purposes.

Although paternity tests are more common than maternity tests, there may be circumstances in which the biological mother of the child is unclear. Examples include cases of an adopted child attempting to reunify with his or her biological mother, potential hospital mix-ups, and in vitro fertilization where the laboratory may have implanted an unrelated embryo inside the mother.